I haven’t held a physical newspaper in quite a while so I am not sure whether my favourites are still in syndication or what new strips are worth reading. My favourite comic strip of all time, however, is Calvin and Hobbes. It is not a punchline-driven strip but a well crafted work of literature with charming characters and wonderful art.
I also enjoy The Boondocks, Fox Trot (though I haven’t read it in years), and The Far Side.