I prefer to know everything. Sure, there are some downsides to it, like the knowledge that most people with my job description earn at least double what I do and the resulting resentment and depression, but the alternative would have far worse downsides.
For instance, I love computers but am in no position to drop thousands of dollars on one. If I were ignorant, I would never have bothered to learn the little bit it takes to keep a Windoze system that costs half as much up and running smoothly, let alone the joys of Linux, so ignorance there would cost me lots of money I don’t have or leave me feeling left behind. Ignorance on cars would force me to go into hock for a car that cost at least ten times as much as the one I have, make me overspend on basic maintenance, and possibly get me a lemon that spends more time in the garage than on the road.
The catch is that casting off your ignorance forces you to think a bit about what is truly important. That requires a bit of effort in order to avoid burning out. For instance, I know full well that the sun is merely a ball of hydrogen that will eventually swell up and incinerate the Earth, but that doesn’t change the fact that a sunset is beautiful, so I can set the 2 H2—> He4 aside and enjoy some quality time on the beach with my wife knowing that neither of us will be alive in 5 Billion years when old Sol goes Red Giant.
Yeah, reality is scary, but only if you let it scare you.
@Blueroses Dr. Manhattan knew everything and yet even he appreciated the beauty of life. Mr Spock knows a lot and yet he still appreciates the company of Captain Kirk and Dr Bones. Data loves his cat and he enjoyed getting laid.
Just because you know everything, that does not necessarily mean that you will be like Marvin the Android from The Hitchhikers Guide to the Galaxy.