From: http://lifehacker.com/#!244497/remove-misspelled-words-from-your-firefox-dictionary
1. Open your application data folder. On XP or Vista, go to your Start menu and hit Run (or just press Windows-R) and paste in %APPDATA%\Mozilla\Firefox\Profiles; on your Mac,
navigate to ~/Library/Application Support/Firefox/Profiles.
2. Find your profile folder, which by default should look something like xxxxxxxx.default.
3. Inside your profile folder, find the file called persdict.dat and open it up in your text editor
of choice.
4 Now just find the misspelling, delete it, and you’re done.
I imagine it’s similar for Opera. Good luck!