If they were to spend a lot of time in the sun they might overheat a little more, but in general, I think no. Fur is fur, and I have a Torti point Siamese who is mottled light brownish gray and white with the Siamese dark paws, but, she has a lot of pale orange dapples too, I worry about her getting skin cancer as white animals are more prone to that. Her nose is pale orange and she has a tiny spot I am watching now.
I think if your kitty has plenty of shade and cold water he will be fine, and, cats are warmth mongers anyway, my cat often likes to sleep on the top shelves in my garage even when it is really hot out.