The best way is to set one thing up that will run itself, and then work on something that requires constant attention. Using my own day as an example, I start my computer up, and it takes 10 minutes to load all the settings. During that time, I set up the coffee pot. While those are running, I put my breakfast into the microwave to cook. Now my computer is ready to load up my browser, and as that is working my breakfast and coffee are ready.
I sit down and eat while I check my e-mails and other messages, then Fluther for a while. When I am finished eating, I rinse all the dishes from the night before and put them in the dishwasher. While it is running, I work on my computer contests (answer questions for points) and take an occasional break to go around the house and pick up the dirty laundry from each room.
When the dishwasher is finished, I separate the laundry and put in the first load, then back to the computer games while the clothes washer and later, dryer run. I alternate between my other daily tasks that way all day. If there is anything I missed on TV, I watch it on Demand or on a disc if my husband has copied it out for me.
If there are any phone calls, I answer them while I put my TV on hold and make appointments with the vet or a repair person.