Yep, I have taken a whole slew.
They all made a difference. Because I needed them. I try to find the nutrients I need in food, but sometimes I have to be realistic and do take supplements. I have a good idea what I am missing. Like D3, it only occurs naturally in mushrooms, milk its usually added in and I lack sunlight.
My family has a propensity to lack B12 absorbtion so I usually can never get enough. And glutamine is an amino acid I am active, and have liver problems.
No one can tell you what you are lacking without testing or taking a look at your diet and history of problems, complaints.
I had the help of a naturalpath to help me get started then did a lot of reading and researching.
Its a rough start but it gets easier over time. And you reap the benefits. You could try taking a multi vitamin. Though there are multi vitamin rating sites. Don’t pick one off the shelf and assume you are getting everything you need. A lot of them don’t get absorbed. The good ones are expensive. I went for mid range one when I was overwhelmed and feeling crappy as I began to feel better I was able to make informed decisions as to what I needed and why as well as dosages.