—I’m sort of LOL at “twinkies’ cream filling may have gone bad”, as if it was ever “good”.
However, @filmfann is otherwise correct. Lead poisoning is a cumulative sort of thing. The only “lead poisoning” that is liable to kill you suddenly is when the lead is in the form of a bullet traveling at high velocity. In other words, you’re not going to die from lead poisoning tonight.
However… given the adulteration of other food products from China… it may not be a bad idea to call a poison control center and talk about symptoms with them. There is a search function at the bottom of this page that can help you locate a nearby center to call. That’s something I would do. But don’t try to diagnose yourself; just tell them what you did and how you feel. If you have the original wrapper (which may contain a production date code, for example), then that might help if there’s a bad batch of Twinkies. Again, I’m trying to imagine a “good” Twinike.