First of all, it’s important to love yourself regardless of how you look. You are unique, special, and probably very loved by at least one person in this world. Ultimately, you should work on loving yourself and then all other good things will flow from that self-knowledge and acceptance.
That being said. Usually if you want to lose fat in one area, you need to work on losing body fat across your whole body. You’re not a Mr. Potato Head with disparate parts—your whole body works together as a system. Daily cardio for 30–60 minutes a day at a decent heart rate (you should be sweating…) will help get you there.
The other side of the equation is eating better. Most processed foods are packed with calories and other satisfying carcinogens. Try eating more fresh vegetables and fruit. Substituting filler foods for vegetables during some meals also helps: a cup of steamed vegetables is roughly 50–70 calories, whereas the same cup of rice is ~250. Those calories add up to several pounds of fat in a year. Also, try to eat more fish and stay FAR AWAY from sodas and sugary drinks. Upping your water intake will also help keep your skin clean and clear.
I use MyFitnessPal to track my calories and watch inspirational shows like Extreme Makeover: Weight Loss Edition to keep me motivated. So far I’ve lost 60lbs and am in the best shape of my life.
So, first and foremost—love yourself. And, if you start feeling sorry for yourself, go visit someone who has lost a leg. That will definitely give you some perspective.
Good luck.