Depends on what’s actually happening, I think. I have had some temporary tooth aches (not very bad ones though) that didn’t mean anything and went away. But the dentists I’ve know have said that tooth pain is an emergency, as a rule, so I’d call one and let them have a look. If the pain’s bad, I’d call immediately. If it’s minor, I’d wait till they open on Monday morning, and hope it goes away before then and/or take some pain reliever.