I used to enjoy several in the regular papers, but I find fewer and fewer funny now. When I was about ten years old, I read a lot of current and older Mad Magazine, and some joke books, and I noticed at some point my patience and interests and tastes shifted – I went from being excited to read a lot of joke comics to them needing to be really funny and not too awful or mean or stupid to me, and so I went from wanting to read 70–80% of them, with lots of endurance, to wanting to read 1–10% of them, with not much endurance.
There are several I’ve always disliked or not found funny, and/or that make me think “what kind of person thinks this is funny or good or thinks like this or thinks to create and read this? I think they must be very strange at best and/or people I would really would not like”.
I am also curious about the situation comedy comics which have been going on for many decades, but the characters never age or change in any way, and where the joke is basically just that the characters are what they are, and are exaggerated and have different points of view. Beetle Bailey is still a private, Sarge is Sarge, and the same General has the same secretary – the author recently died, but the same old comics keep coming, every (?) day for 67–68 years… Blondie is still surprised by Dagwood’s sandwich size. Families never age. The Family Circus is still in family hell. All of them are trapped in time-loop dimensions where they don’t realize they are repeating their same life situation forever. They must all have offended the gods or Time Lords severely.
(I do generally get the ones you mentioned: Non Sequitur, Doonesbury (can take a lot of context), Dilbert (takes IT work context), and Peanuts.)