Generally, it is the potency.

People will claim that tequila will make them more aggressive or crazier, but really, that has more to do with shooting it rather than sipping it over twenty to thirty minutes. Shoot gin or whiskey and it will make you just as crazy as tequila.

Wine is usually drunk more leisurely, same with beer. So you get drunk more gradually.

Yeah. Alcohol content, is the main variable.

Illicit stills still elicit blithely blinding effects notwithstanding the worm in the mezcal.