I have yet to find one with a regular show that is worth the time when it comes to humor. The last one was probably Johnny Carson. Other comics that I believe are good are Gallagher, Brad Williams, and Bob Saget (R.I.P.). Redd Foxx, Eddie Murphy, and Richard Prior were hilarious as well. But all of those, with the exception of Gallagher, I would not want to watch with small children in the room.
“Something different” is not clear what I meant.
For example which ones address this: https://www.youtube.com/watch?v=Lsl73twV1ZM Navratilova, Jenner and others regarding swimmer Thomas (last name) in competition with women. (Edited)