Not really. There are a couple possibilities:
1) Iran and its allies are primarily Shi’ite muslims, while the rest of the muslim world is overwhelingly Sunni. There is no great love between the two factions; they have fought before. It is concievable that they will war again. Thrown in Islamic Jihad, What remains of ISIS, what remains of Al Qaeda, there could be more Arabs killing Arabs.
2) Internal dissension in Saudi Arabia – MBS has liberalized quite a bit (although not enough) and there are plenty of arch-conservative Wahabis that would prefer going back to the ‘old’ super-religious way of life. There is probably some risk of them rising up. Although because of the strength of the internal security forces, not a bad thing.
3) Russia could get tired of MBS and poison him like they have done with others. This would likely be if MBS got close to the United States again.
4) Israel could assassinate MBS if they felt threatened, although this seems unlikely because Israel will achieve more with MBS in power and as a friend.
There’s no imminent threat, but that doesn’t mean some crazy couldn’t come along – like they did in 1975 when King Faisal was assassinated. link