Potentially. With lots of laxitives and BMs. Flush that food right on thru you before your body has a chance to absorb anything from it….
You can also lose weight w/ urination…if your weight gain is from water retention. W/ diuretics you can lose the weight.
I also like Laureth’s suggestion. Exercise via potty breaks.
However, in general, without these extreme examples, the answer is no….