My experience, and I know others have experienced the same, is that nationwide banks have some disadvantages over small local banks. Local banks are likelier to try hard to give you good service, because you are one of a smaller number of customers. Local banks are likelier to keep your money circulating in the local community, helping your neighbors’ businesses, instead of sending it far away (if you care about that sort of thing). Though this is less reliable than it used to be—you can ask the bank when you go in to interview them about opening an account.
A drawback is that interest earned may be lower, and loan rates charged may be higher. But some people are willing to except this on balance.
If you are so progressive that you would like to strengthen the least capitalist part of the economy, use a credit union instead of a bank. Credit unions are non-profit organizations (which is why commercial banks hate them, and push legislation to restrict what they can do). Once again, you may find higher loan rates and lower savings account interest than at a commercial bank. You may also find that the staff, while eager to be helpful, are a little less skilled than employees of a commercial bank. But to a progressive, it’s worth it.