Edna Bay, Alaska (www.ednabayalaska.net). Population of about 50 on a remote Alaskan island, 60 miles west of the continental mainland, with no means of access other than private boat or seaplane. Closest town with services such as banks, restaurants, lodging, doctors, etc, is Craig, Alaska which is a 40 mile trip by boat south from Edna Bay through waters that can get very rough when the weather picks up – which can happen often. You can’t get much more remote than this in the USA.