I have a hard time with powder detergents in general. They seem to leave more of a residue, which is very irritating to my skin. If it does not wash out completely, I get very red, itchy rashes. I do best with unscented liquid detergents.
I have similar reactions to any kind of soap that contains a perfume. Or perfumes in general; my wife bought me a bottle of cologne once, and after a lot of prodding, I wore it one day. It gave me a horrible rash.