Live on, or as close to campus as you can. There is a lot that one learns in college that isn’t a part of the curriculum.
Don’t go home every weekend. See the previous point
Make friends outside of your major.
Don’t be afraid to change major or to take a while to declare. The people all around you who “have known since kindergarten that they wanted to . . .” will often be the first to change majors.
Especially if you are in a large university, find a few clubs/sports/activities to be a part of.
No matter what they are giving away, do not sign up for a credit card. Student loans will be enough of a debt load to get our from under in four years. Don’t make things worse with a load of credit card debt on top of it.
Find out from people in your major what the difficult classes will be. Try to spread them out so that you don’t really get hammered in a single semester.
Find out what a professor is really interested in and take the class that they teach on that. It will be one of the best classes that you have taken because the professor’s enthusiasm will be contagious.
Schoolwork is important. People are more important. Do not neglect personal relationships for schoolwork.
Date rape is real. Only drink a drink that YOU opened. Don’t let an open drink or cup out of your sight.