I was diagnosed bi-polar at age 39. I don’t know if it developed at that late age because I always had it and was mis-diagnosed, or if it developed as a result of the Traumatic Brain Injury that I suffered in 1992. I went on it to treat the bi-polar depression I have and also to help me sleep. I wasn’t happy about taking it at first because of the possible side effects it has, but I now depend on it to sleep. I was ok on 100 and then 200 mg, but when my doctor tried 300 mg my throat swelled and I couldn’t breathe. He put me on another medicine that protected me from the breathing problems and I went back to 200 mg along with the new medication. Has anyone else had a reaction like this to Seroquel and how did they deal with it?