I’m late to answering this Q, but:
I think it’s yes and no.
Yes, because there are things like carpel tunnel, tendonitus, where extremely repetitive motions will wear out a specific part of the body.
But also No, because aside from that extreme and pinpointed overuse, (as long as they’re doing something to damage the body) the more active a person is, the longer they live.
So I think it’s hard to compare to mileage, because that’s not what’s going on. Like others say, we age, something cars don’t do.
If we didn’t age, and we didn’t overstress a single point to our body, the process would be something like this: our body would get torn up, repair itself, torn up, repair itself, on and on in an endless process.
Our bodies are built to fix themselves, and fix themselves better. (Get a blister, a callous grows.)(Work out, and you’re micro-tearing the muscle so it can grow back stronger. Stretch, grow back longer.)
Food/fuel aside—
The more we work, the more our body will tune itself to that work. Give the body its needed time to adjust, and we can do anything for any length of time.
Except fly… that’s what planes are for…