I think it depends too on what genes you are interested in. Hip dysplasia is a recessive gene, it can crop up anywhere and can disappear for generations,. If you are referring to the look of the dog really that isn’t much different. I look like my grandmother did at the same age but my mother did not.
You can have a cross breed dog develop hip dysplasia, genetic problems are not solely found in line bred or even in bred dogs or cattle or horses. The probability of it showing up can be greater but the theory is that it reproduces the best genes as well as the less desirable ones. Breeders who practice it extensively should be prepared to cull.
Bouvier pedigrees are available for many generations back and it is interesting to note when a pup is born that so greatly resembles a great, great, great grandparent, they seem to be cloned. It is an intriguing subject.