The type of work people do will change. In @CyanoticWasp‘s example, he talks about doing interior decorating. The difference between jobs now and jobs then is that, with the gruntwork jobs taken care of, humans will be free to do the creative work. Everything that we do will become an art form.
You know the saying, “content is king?” Most of the jobs in the world will eventually become about content. But there’s a long way to go before that happens. The change will happen first in the most developed parts of the world—but I don’t know what countries will be the most developed at that point.
In any case, I think we will start seeing this happen at a faster and faster rate. Already all the grunt jobs are moving out of the US. There are a few sectors of the economy that are expanding even in the recession. Health care is one I can think of, and entertainment is the other. Oops. Shooting off my mouth on that one. I’m guess entertainment is still growing.
Move into content, and you’ll have a future. Hey! Guess what? Everyone on fluther is creating content! We’ve got a leg up. Although, as @CyanoticWasp and @Coloma note, you’ll most likely be needing to keep yourself employed. The creative professions or activities are full of individuals seeking to hit it big. It’s entrepreneurialism at its finest.
Of course, people like me who don’t have an entrepreneurial bone in their bodies are going to be SOL, anyway.